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New Natural Compounds purified in Antibiotics Lab, RIKEN

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* : re-discovered compounds as new bioactive roles other than previously reported.

A | C | E | G | I | L | M | N | P | Q | R | S | T | X

 

Compound name
Biological activity
Producing organism
Year reported
Details   

A

acetophthalidincell cycle inhitionAspergillus sp.

1996

 actiketalmitogenStreptomyces pulberaceus subsp. epiderstagenes

1991

albopeptin antimicrobialStreptomyces albofaciens

1986, 92

ascamycinantibacterialStreptomyces sp.

1984

azaspireneantiangiogenesisNeosartorya sp.

2002

C

cationomycin A - Dantimicrobial Actinomadura azurea

1981-83

 curvularol cytotoxic Curvularia sp.

2001

cyclotryprostatin A - Dtubulin assemble inhibitionAspergillus fumigatus 

1995

cytotrienin A, B apoptosis-inducingStreptomyces sp.

1997

cytovaricincytostaticStreptomyces sp. 

1981

cytoxazone cytokine modulator Streptomyces sp. 

1998

E

ECH *Fas-mediated apoptosis inhitibitor uncharacterized fungus 

2003

 enamidonin flat reversion activity of v-src transformed cellsStreptomyces sp. 

1995

enopeptin A anti-bacteriophage activity Streptomyces sp. RK-1051 

1991

epiderstatin anti-mitogenic activity Streptomyces pulveraceus subsp. epiderstagenes 

1989

epolactaene induction of neurite outgrowth Penicillium sp.

1995

epoxyquinol A, B angiogenic inhibitor uncharacterized fungus

2002

epoxytwinol A angiogenic inhibitor uncharacterized fungus 

2005

G

guanine 7-oxideantitumorStreptomyces sp.

1985

I

iso-avenaciolide * phosphatase inhibitorAspergillus sp.

2002

 isoxazole 4-carboxylateherbicidalStreptomyces sp.

1991

L

lipopeptin A - C antimicrobialStreptomyces sp. 

1980

 liposidomycin B, C antibacterical, inhibition of peptideglycan synthesis Streptomyces griseosporeus 

1988-89 

lucilactaene cell cycle inhibition Fusarium sp. 

2001

M

malolactomycin A antifungal Streptomyces sp. 83-634

1993

N

neopeptin inhibition of fungal cell wall synthesis Streptomyces sp. 

1986

P

phoslactomycin A - F phosphazomycin C1, C2  inhibitor of protein phosphatase 2A Streptomyces sp. 

1985

 phosmidosine antifungal Streptomyces sp. RK-16 

1991

 

phosphatoquinone A, B inhibitor of protein tyrosine phosphatase Streptomyces sp. 

1999

 

pironetin * tubulin disassembler Streptomyces sp. 

1999

 

polyoxin A - M inhibition on fungal cell-wall synthesis Streptomyces cacaoi ver. asoensis 

1968-72 

 

Q

questiomycin A, B antimicrobialStreptomyces sp.

1965

 

R

respinomycin A - D induction of cell differentiation  Streptomyces xanthocidicus  

1991-93 

 

 reveromycin A - D antifungal, cytotoxic Streptomyces sp. SN593 

1990-92 

 

RK-286C, D inhibitor of protein kinase C Streptomyces sp. RK-286 

1990

 

RK-397 antifungal Streptomyces violaceusnigar 

1993

 

RK-682 * phosphatase inhibitor Streptomyces sp. 

1995

 

RK-1009--- Streptomyces sp.  

1998 

 

RK-1409 inhibitor of protein kinase C Streptomyces platensis subsp. malvinus RK-1409 

1992

 

RK-1441A, B antibacteriophage Streptomyces sp. 

1990 

 

RK-805 inhibitor of methionine aminopeptidase 2Neosartorya sp. 

2004

 

RK-95113 antiogenesis inhibitor Aspergillus fumigatus 

2006

 

RS-22A, B, C antimicrobial Streptomyces violaceusnigar 

1995

 

S

sangivamycin *  inhibitor of protein kinase C Streptomyces sp. 

1989

 

 sparoxomycin A1, A2 flat reversion activity of v-src transformed cells Streptomyces sparsogenes 

1996

 

stevastelin * Phosphatase inhibitor Aspergillus sp. 

1997

 

T

tautomycetininhibition of protein phosphatase Streptomyces sp. 

1989

 

 tautomycin inhibition of protein phosphatase Streptomyces sp. 

1987

 

terpendole E * cell cycle inhibition inhibition of kinesin Eg5 Albophoma yamashiensis 

2003

 

terpeptin cell cycle inhibition Aspergillus terreus 

1997

 

trichostatin RK-- Streptomyces sp. RK98-A74

2001

 

tryprostatin A,B 
spirotryprostatin B
tubulin assemble inhibition Aspergillus fumigatus 

1995

 

X

xanthostatin antibacterial Streptomyces sp. 

1987

 

 

 
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